Use the Zoom pane of Accessibility System Preferences to make the entire screen larger or to enlarge just the area where the pointer is located.
To open this pane, choose Apple menu > System Preferences, click Accessibility, then click Zoom.
Use keyboard shortcuts to zoom
Use the listed shortcuts to zoom in and out. For example, to zoom in, press Option-Command-Equal Sign.
Use scroll gesture with modifier keys to zoom
Hold down the selected modifier key while scrolling with your trackpad or the scroll wheel on your mouse.
For example, with the default trackpad settings, press and hold the Control key and drag two fingers up (to zoom in) or down (to zoom out).
Make zoomed images appear smooth.
Zoom follows the keyboard focus
Magnify the area that has the keyboard focus.
Enable Touch Bar zoom
Speak items under the mouse
Have your Mac identify items under the pointer only when you use zoom or all the time.
You can set whether to have your Mac wait a shorter or longer time before speaking.
Zoom the entire screen (Full screen) or just the area where the pointer is located (Picture-in-picture).
Specify options for full-screen or picture-in-picture zoom.
You can enable keyboard shortcuts for some zoom options in the Accessibility section of the Shortcuts pane of Keyboard preferences. To open the pane, choose Apple menu > System Preferences, click Keyboard, then click Shortcuts.