To resolve this issue, update to iOS 6.1.2.
iOS 6.1: Excess Exchange activity after accepting an exception to recurring calendar event
When you respond to an exception to a recurring calendar event with a Microsoft Exchange account on a device running iOS 6.1, the device may begin to generate excessive communication with Microsoft Exchange Server. You may notice increased network activity or reduced battery life on the iOS device. This extra network activity will be shown in the logs on Exchange Server and it may lead to the server blocking the iOS device. This can occur with iOS 6.1 and Microsoft Exchange 2010 SP1 or later, or Microsoft Exchange Online (Office365).
* An exception is a change to a single instance of a repeating calendar event.