If the question mark appears only momentarily before your Mac starts up normally:
- Reset NVRAM.
- Make sure that your preferred startup disk is selected in Startup Disk preferences.
If the question mark persists, follow these steps:
- Press and hold the power button on your Mac for up to 10 seconds, until your Mac turns off.
- Turn on your Mac and immediately press and hold Command (⌘) and R to start up from macOS Recovery.
- While in macOS Recovery, use Disk Utility to repair your startup disk.
- If Disk Utility found no errors or repaired all errors, reinstall macOS.
- If you still need help, please contact Apple Support.