iTunes for Windows: "iTunes might be unable to launch or communicate with iPod or iPhone" message
Products Affected
iTunes 7 for Windows, iTunes 8 for Windows, Windows XP
Symptoms
When opening iTunes for Windows, you may see the following message:
"iTunes might be unable to launch or communicate with iPod or iPhone. For help repairing your operating system, click More Information."
Resolution
This symptom may be caused by an issue with the digital signing of Windows XP drivers. First, update to the latest version of iTunes. You can download the updater from the iTunes download page or, in iTunes, choose Help > Check for Updates.
If the issue continues with the latest version of iTunes, try following the steps below to reregister several .dll files, which may resolve this issue.
- Quit iTunes.
- Highlight all of the following 10 lines of text that begin with regsvr32 and then choose Copy from the Edit menu of your web browser:
regsvr32 /s softpub.dll
regsvr32 /s wintrust.dll
regsvr32 /s dssenh.dll
regsvr32 /s rsaenh.dll
regsvr32 /s gpkcsp.dll
regsvr32 /s sccbase.dll
regsvr32 /s slbcsp.dll
regsvr32 /s mssip32.dll
regsvr32 /s cryptdlg.dll
regsvr32 /s initpki.dll
- Open the Notepad program by choosing
Start > All Programs > Accessories > Notepad. - In Notepad, choose Paste from the Edit menu. Note: make sure that the text that appears in Notepad is the same as what is shown above.
- From the File menu, choose Save As.
- In the File name field type appleitunes.bat and save the file to the Desktop.
- Close Notepad and locate the appleitunes.bat file. It should appear on the Desktop with the icon shown below:

- Double-click the file and you will see a black window appear on the screen for about a minute. Wait until the window automatically disappears and proceed to the next step.
- The appleitunes.bat file can be deleted at this time.
- Open iTunes.
Additional Information
Because some malware may unregister the .dll files, make sure you have the most recent updates to your anti-virus software and then do a full scan of your files.
For additional information, please see the following article:
iTunes displays -50 error message when syncing iPod on Windows XP
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